After 6-24 h after the operation, the patients were given 250 mL of 5% glucose saline orally

May 27, 2023 p38 MAPK

After 6-24 h after the operation, the patients were given 250 mL of 5% glucose saline orally. of nutritional indexes was also evidently better in the ENN group. Immune function was evidently improved compared with the CG. The level of inflammatory reaction factors was also evidently lower in the ENN group, and the incidence of postoperative complications was evidently lower than that of the CG, and the physical recovery was also better than that of the CG (P 0.05). Conclusion: ENN for patients with colon carcinoma can improve their immune function, improve their nutritional level and promote their physical recovery. strong class=”kwd-title” Keywords: Colon carcinoma, early enteral nutrition, immune function, nutrition level, recovery Introduction Colon carcinoma [1] is a common malignant tumor, and its pathogenesis is not clear, but many research reports suggest that it is related to risk factors such as high pressure in life, lack of exercise, more entertainment, lack of fresh vegetables and fruits, and eating too much fatty food [2]. It is often divided into the categories of lump, infiltration and ulcer in the medical center, and is divided into adenocarcinoma, mucinous carcinoma and Prkwnk1 undifferentiated carcinoma histologically, among which adenocarcinoma is the most Emiglitate common and undifferentiated carcinoma has the worst prognosis. In the medical center, the symptoms of colon carcinoma are usually distinguished from the remaining and ideal colon, and abdominal pain, abdominal mass, intestinal obstruction, and changes in stool practices and stool characteristics are common symptoms [3,4]. The proliferation of malignant tumor cells causes the bodys nourishment to be constantly consumed. In addition, anorexia, pain and additional reactions can lead to different examples of malnutrition and decreased immune function in tumor individuals. Postoperative fasting further aggravates the bad nitrogen balance and affects immune function [5]. At present, the main treatment for colon carcinoma is still radical surgery [6]. Intestinal obstruction isn’t just a symptom of colon carcinoma patients, but is also a complication of colon carcinoma. It usually causes poor stool discharge or failure to defecate, abdominal distension, nausea and vomiting, resulting in poor hunger or failure to eat, which will cause malnutrition and decreased immunity for a long time. Particularly, intestinal obstruction caused by colon carcinoma is definitely often complicated with chronic blood loss and anemia, thus aggravating the above symptoms and resulting in slow healing of the postoperative incision, improved incidence of anastomotic leakage and additional complications, and it affects numerous organs of the whole body, increasing medical risk and postoperative mortality [7,8]. Parenteral nourishment [9] has always been used as the main nutritional method after Emiglitate colon carcinoma surgery. However, according to reports, long-term use of parenteral nourishment, especially during fasting after surgery, will cause intestinal mucosa atrophy and damage the intestinal mucosal barrier. Emiglitate In recent years, it is advocated to use enteral nourishment in the early postoperative period [10]. Early postoperative enteral nourishment for individuals with gastrointestinal carcinoma is definitely superior to parenteral nourishment in promoting the recovery of immune suppression caused by surgical stress, especially in cellular immunity Emiglitate [11]. Therefore, the early use of enteral nourishment combined with parenteral nourishment after colon carcinoma surgery is helpful for individuals recovery [12]. In this study, the above two methods were used after colon carcinoma surgery, and the effects of the two methods on immune function and physical recovery of individuals were compared. Data and methods Research participants A total of 97 individuals with colon carcinoma from November 2018 to November 2019 were randomly grouped into the control group (CG) and the early enteral nourishment support group (EEN group). There were 40 instances in the CG, including 22 males and 18 ladies, aged (58.65.1) years. There were 57 instances in the ENN group, including 34 males and 23 ladies, aged (59.15.7) years. Inclusion criteria were as follows: patients were diagnosed by colonoscopy before operation and confirmed by pathology after operation; individuals did not receive radiotherapy and chemotherapy before operation; no albumin or immunopotentiator was used within 2 weeks before operation; patients or their families authorized the educated consent; the study was authorized by the Ethics Committee. Exclusion criteria were as follows: individuals with severe liver and kidney dysfunction; individuals with congenital irregular amino acid rate of metabolism or those complicated with additional metabolic diseases and allergic diseases; individuals with diabetes and thyroid dysfunction;.