The modes of education for teaching our students and residents are also undergoing a change with the use of virtual meetings and e\learning programmes. newly infected people in the pandemic. It may either be that writing articles is contagious or C and this is more likely C that some doctors just have more time in front of the computer than working full speed in their offices or hospitals. We now know that the skin is also affected in a variable proportion of patients with COVID\19, estimated to be between 2% and 20%. 1 , 2 , 3 The clinical symptoms are manifold and unfortunately, they are not always described precisely, often becoming referred to as rash. If one was to presume that this rash is an exanthematous maculopapular eruption, then one offers to notice that beyond the common description, the morphology of skin lesions is quite colourful, often permitting only a descriptive analysis. Skin lesions explained and reported so far have been urticarial, vesicular, pustular, eczematous, acropapular, purpuric, livedoid, chilblain\like while others (see the COVID\19 Unique Forum in every issue of our Journal). Sometimes, classical infectious pores and skin diseases may be triggered or elicited like herpes simplex or varicella\zoster illness. Of course, the many possible forms of drug hypersensitivity including severe cutaneous adverse reactions (SCAR) must be specially regarded as. Of special interest as the skin manifestations that are potentially and specifically related to the COIVD\19 is the event of vascular lesions, become they purpura, livedo, vasculitis or chilblain\like changes on your toes and toes of many individuals. 4 , 5 However, very similar pores and skin lesions have also been observed in additional individuals living in the same area during the same BMP3 period but without SARS\CoV\2 as confirmed by PCR checks. Some of these individuals, however, were proven to be positive with IgG or IgA antibody checks, providing floor to the assumption they had already conquer the infection. So far little is known about mechanisms in pathophysiology leading to these events. Even though coronavirus itself has not yet been recognized in the skin, the manifestation of the angiotensin\transforming enzyme 2 (ACE2) receptor was recognized not only on endothelium but also in pores and skin tissues, especially in keratinocytes. 6 We learn every day something fresh; it is definitely a time of quick growth of info. A variety of pathological conditions have been named as risk factors such as age, diabetes, obesity, cardiovascular disease, hypertension, lung diseases and smoking. Whether oncological diseases, such as pores and skin tumor, or inflammatory pores and skin diseases, such as psoriasis or atopic eczema, are affected and exacerbated from the disease is not known. The part of medications given is also under conversation. Should immunosuppressants like methotrexate and cyclosporin in autoimmune diseases, cytostatics in lymphoma, biologics like checkpoint inhibitors in melanoma, or TNF and additional cytokine antagonists in psoriasis become stopped? Some expert groups have given position statements to these topics, mostly providing general recommendations to be careful during the active phase of illness C but do not generally quit immunomodulating treatment. 7 , 8 Inflamed pores and skin might be an easier target for viral illness. Ademetionine disulfate tosylate Apart from the pores and skin of our individuals, we ought to also take care of ourselves, that is to say, the skin of many healthcare workers, doctors and nurses in private hospitals, care homes and offices. Ademetionine disulfate tosylate They have to follow stringent hygiene rules, including frequent disinfection methods and hand washings, which are providing rise to instances of hand eczema especially.Reflecting on this, I am thankful to survive and that I have the chance for the second time in my life to witness the emergence of a new disease spreading over the world. that writing articles is definitely contagious or C and this is definitely more likely C that some doctors just have more time in front side of the computer than working full speed in their offices or private hospitals. We now realize that the skin is also affected inside a variable proportion of individuals with COVID\19, estimated to be between 2% and 20%. 1 , 2 , 3 The medical symptoms are manifold and regrettably, they are not always described exactly, often being referred to as rash. If one was to presume that this rash is an exanthematous maculopapular eruption, then one has to notice that beyond the common description, the morphology of skin lesions is quite colourful, often permitting only a descriptive analysis. Skin lesions explained and reported so far have been urticarial, vesicular, pustular, eczematous, acropapular, purpuric, livedoid, chilblain\like while others (see the COVID\19 Unique Forum in every issue of our Journal). Sometimes, classical infectious pores and skin diseases may be triggered or elicited like herpes simplex or varicella\zoster illness. Of course, the many possible forms of drug hypersensitivity including severe cutaneous adverse reactions (SCAR) must be specially regarded as. Of special interest as the skin manifestations that are potentially and specifically related to the COIVD\19 is the event of vascular lesions, become they purpura, livedo, vasculitis or chilblain\like changes on your toes and toes of many individuals. 4 , 5 However, very similar pores and skin lesions have also been observed in additional individuals living in the same area during the same period but without SARS\CoV\2 as confirmed by PCR checks. Some of these individuals, however, were proven to be positive with IgG or IgA antibody checks, providing ground to the assumption they had already overcome the infection. So far little is known about mechanisms in pathophysiology leading to these events. Even though coronavirus itself has not yet been recognized in the skin, the manifestation of the angiotensin\transforming enzyme 2 (ACE2) receptor was recognized not only on endothelium but also in pores and skin tissues, especially in keratinocytes. 6 We learn every day something fresh; it is a time of rapid growth of information. A variety of pathological conditions have been named as risk factors such as age, diabetes, obesity, cardiovascular disease, hypertension, lung diseases and smoking. Whether oncological diseases, such as pores and skin tumor, or inflammatory pores and skin diseases, such as psoriasis or atopic eczema, are influenced and exacerbated by the virus is not known. The role of medications given is also under conversation. Should immunosuppressants like methotrexate and cyclosporin in autoimmune diseases, cytostatics Ademetionine disulfate tosylate in lymphoma, biologics like checkpoint inhibitors in melanoma, or TNF and other cytokine antagonists in psoriasis be stopped? Some expert groups have given position statements to these topics, mostly giving general recommendations to be careful during the active phase of contamination C but do not generally quit immunomodulating treatment. 7 , 8 Inflamed skin might be an easier target for viral contamination. Apart from the skin of our patients, we should also take care of ourselves, that is to say, the skin of many healthcare workers, doctors and nurses in hospitals, care homes and offices. They have to follow rigid hygiene rules, including frequent disinfection procedures and hand washings, which are giving rise to cases of hand eczema especially in persons with sensitive skin. Adequate skin protection and skincare with the right type of emollients is crucial. Moreover, the Ademetionine disulfate tosylate adverse effects of protective clothing, masks and gloves have to be considered 9 , 10 ; acneiform eruptions, irritative dermatitis and miliaria, just to name a few, have been reported. The pandemic also influences the way dermatology is usually practised in the offices and hospitals. 11 , 12 Teledermatology and telemedicine are gaining momentum. The modes of education for teaching our students and residents are also undergoing a change with the use of virtual meetings and e\learning programmes. Some associations are now organizing entirely virtual meetings and conferences, such as EADVs annual congress that had been planned to take place in Vienna this autumn. We immediately made the decision that these topics are important and should be featured in JEADV. We started a fast\track peer\evaluate.
